Red blue wave tight

Intraneuron for clinical practices

A neurologist in his fifties talking with an older patient in a bright consulting room

Beyond Memory Exam

Most people arrive here looking for the Memory Exam, the at-home cognitive screening test, completed entirely by voice, we sell directly to the public. That is one of the two things we do.

The other is building and operating the software that community neurology practices use to deliver dementia care at scale. If you are a practice, a health system or a research site, this page is for you.

The CMS GUIDE model

GUIDE, Guiding an Improved Dementia Experience, is a Centers for Medicare and Medicaid Services model for delivering coordinated dementia care. Participating practices take on structured responsibilities around assessment, care planning, caregiver support and ongoing follow-up.

Meeting those responsibilities consistently, for every patient, is an operational challenge before it is a clinical one. Intraneuron implements and operates the software workflow that makes it repeatable.

A Latina woman in her fifties and her father in his seventies listening to a pharmacist pointing something out on a box
A Black woman in her seventies waiting in a bright airy reception, coat on lap

What the platform handles

  • Registration and intake. Patients complete registration and intake forms before they arrive, so the visit starts with the paperwork already done.
  • Medical and neuropsychological scales. These are instruments a practice already relies on, administered and scored consistently rather than re-keyed from paper.
  • Audio questionnaires. Scales administered by voice, which is how we measure verbal memory and fluency and what makes remote administration practical for older patients.
  • Caregiver-reported measures. These are collected as part of the same process rather than chased separately.
  • Structured follow-up. Workflow tracks where each patient is, so scheduled reassessment happens instead of depending on your patients remembering to schedule.
  • Embedded clinical trial recruitment. This service helps identify candidates for research out of routine care, rather than running recruitment as a separate effort.

These are components rather than a fixed product. Practices differ, and so do the pathways they need, so we build the workflow a practice runs rather than asking it to adopt ours. We built your system for you.

This is the work described in Implementing the CMS GUIDE Dementia Care Model in a Community Neurology Practice with Digital Tools, Standardized Scales and Embedded Clinical Trial Recruitment, published in Neurology in 2026.

Memory clinic workflow

We also provide the workflow infrastructure behind memory clinics: intake, structured assessment, scoring, reporting and scheduled follow-up, organized so a clinic runs the same pathway for every patient instead of assembling one per visit.

A practice running a memory clinic and a practice participating in GUIDE are doing much the same operational work, and both are better served by software built for the pathway rather than by a general-purpose record system.

A white man in his seventies with a printed report and a pen on a kitchen table
Two old friends in their seventies hanging washing out in the afternoon sun

Peer-reviewed

To note, Memory Exam, our voice-recognition cognitive screening, has been evaluated against standard neuropsychological assessment and published in peer-reviewed journals.

  • Convergent Validity between Standard Neuropsychological Assessment and Web-Based Voice-Recognition Neuropsychological Assessment. Archives of Clinical Neuropsychology, September 2024.
  • Convergent Validity and Classification Agreement Between Traditional Cognitive Screening Instruments and a Novel, Electronic-based, Voice-recognition Cognitive Screening Tool. Neurology, April 2024.
  • Hal, do I have memory problems? A pilot study investigating a voice recognition cognitive screening tool. Alzheimer's & Dementia, December 2021.

The underlying technology is covered by United States patents 11,547,345 and 12,226,221.

Who built it

Intraneuron was founded in 2013 by Gregory Sahagian, M.D., a neurologist and chief executive of The Neurology Center of Southern California, and Vidar Vignisson, a technology executive with more than 30 years building software.

The platform is developed alongside practicing clinicians, including two board-certified clinical neuropsychologists. You can read more about the team.

An Asian man in his late sixties at a library table with afternoon light across it
A white woman in her fifties turning down a radio to hear the other person better

Let's talk

If you are evaluating Intraneuron for a practice, a health system or a research site, email info@intraneuron.com and tell us what you are trying to solve.

We are based in San Diego, California. We look forward to getting to know you.

Where to go next

If you are evaluating Intraneuron for a practice or a health system, let's have a conversation.

You can also read about the team, the company, or the normative study we are running.

Get in touch
A white man in his seventies tending plants on a sunny balcon